Enables the long term expansion of embryonic stem cells (ESC) without the addition of MEF, LIF, and FBS while retaining pluripotency. ESC's treated with ID-8 in a serum-free medium consistently differentiated into many cell types, including neurons, muscle cells and hepatocytes. Stimulates proliferation at a steady rate.
Product Details
| Alternative Name: | 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol |
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| Formula: | C16H14N2O4 |
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| MW: | 298.3 |
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| CAS: | 147591-46-6 |
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| Purity: | ≥98% |
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| Appearance: | Yellow solid. |
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| Solubility: | Soluble in DMSO (20 mg/ml). |
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| Shipping: | Shipped on Blue Ice |
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| Short Term Storage: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 6 months after receipt when stored at -20°C. Solutions can be stored at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Indole Derivatives sustain Embryonic Stem Cell Self-Renewal in Long-Term Culture: T. Miyabayashi, et al.; Biosci. Biotechnol. Biochem.
72, 1242 (2008),
Abstract;
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