Product Specification
| Alternative Name: | MC2R |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to aa 87-99 of human MC2R (melanocortin receptor 2). |
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| UniProt ID: | Q01718 |
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| Species reactivity: | Human, Rat
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| Applications: | IHC, WB
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| Purity Detail: | Affinity purified. |
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| Formulation: | Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.05% sodium azide. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | The melanocortin receptors are members of the G protein-coupled receptor superfamily. Their ligands, the melanocortins, are peptides consisting of α-, β- and γ-melanocyte stimulating hormone and adrenocorticotropic hormone. MC2R is only activated by ACTH. It is expressed gene is expressed in skin, scalp tissue, compound nevus tissue, basal cell carcinoma tissue, and cultured melanocytes. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation: S. Hafiz, et al.; Int. J. Oncol.
41, 1373 (2012),
Application(s): Immunofluorescence,
Abstract;
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