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Melanocortin receptor 2 (extracellular) polyclonal antibody

BML-SA639-0200 200 µl 757.00 USD
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Product Details

Alternative Name:MC2R
Immunogen:Synthetic peptide corresponding to aa 87-99 of human MC2R (melanocortin receptor 2).
UniProt ID:Q01718
Species reactivity:Human, Rat
Applications:IHC, WB
Purity Detail:Affinity purified.
Formulation:Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.05% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:The melanocortin receptors are members of the G protein-coupled receptor superfamily. Their ligands, the melanocortins, are peptides consisting of α-, β- and γ-melanocyte stimulating hormone and adrenocorticotropic hormone. MC2R is only activated by ACTH. It is expressed gene is expressed in skin, scalp tissue, compound nevus tissue, basal cell carcinoma tissue, and cultured melanocytes.
Regulatory Status:RUO - Research Use Only

Product Literature References

Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation: S. Hafiz, et al.; Int. J. Oncol. 41, 1373 (2012), Application(s): Immunofluorescence, Abstract; Full Text
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