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Calcium sensing receptor (extracellular) polyclonal antibody

 
BML-SA637-0050 50 µl 376.00 USD
 
BML-SA637-0200 200 µl 571.00 USD
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Product Specification

Alternative Name:CaSR
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 216-229 of human CaSR (calcium sensing receptor).
 
UniProt ID:P41180
 
Species reactivity:Human, Mouse, Rat
 
Applications:Flow Cytometry, ICC, WB
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:CaSR is a member of subfamily C of the G-protein-coupled receptor superfamily. As its primary role, CaSR is a key player in calcium homeostasis and is expressed in tissues involved in calcium metabolism, such as parathyroid cells and kidney. CaSR activation is followed by a rapid, transient increase in the cytosolic calcium concentration, resulting from mobilization of calcium from thapsigargin-sensitive intracellular stores, as well as an increased calcium influx through voltage-insensitive calcium channels located at the cell membrane. CaSR regulates cellular processes such as proliferation, apoptosis, and differentiation under both normal and pathologic conditions.
 
Regulatory Status:RUO - Research Use Only
 

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