| Alternative Name: | Transient receptor potential cation channel subfamily V member 2 |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to aa 735-750 of rat TRPV2. |
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| UniProt ID: | Q9WUD2 |
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| Species reactivity: | Mouse, Rat
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| Applications: | WB
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| Formulation: | Lyophilized from PBS, pH 7.4, 1% BSA and 0.05% sodium azide. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Although it shares around 50% homology with TRPV1, TRPV2 is not activated by capsaicin or by protons. It has a high temperature threshold of ~52°C and is considered to play an essential role in the perception of high-intensity noxious heat stimulation. TRPV2 is also considered to be a stretch-activated channel and to play a role in skeletal and cardiac muscle degeneration and pain pathway. TRPV2 is expressed in DRG neurons, different brain regions and non-neuronal tissues such as spleen, lung and intestine and in components of the immune system. |
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| Regulatory Status: | RUO - Research Use Only |
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