| Alternative Name: | BACE, β-Secretase, β-Site APP cleaving enzyme 1, Memapsin-2, Aspartyl protease 2 |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to the catalytic domain of human BACE1 (BACE, ß-secretase). |
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| UniProt ID: | P56817 |
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| Species reactivity: | Human, Mouse, Rat
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| Crossreactivity: | Does not cross-react with BACE2. |
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| Applications: | WB
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| Formulation: | Liquid. In PBS containing 0.05% sodium azide and 50% glycerol. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | BACE1 is expressed as a pre-pro-aspartyl protease, sometimes glycosylated, and inserted into the cell membrane as a dimer with catalytic domains in the cytosol. It is implicated in angiogenesis and Alzheimer’s disease. |
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| Regulatory Status: | RUO - Research Use Only |
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