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[pSer52]Eukaryotic Initiation factor 2 α polyclonal antibody

BML-SA405-0020 20 µl 184.00 USD
BML-SA405-0100 100 µl 679.00 USD
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Product Details

Alternative Name:eIF2α
Immunogen:Synthetic peptide corresponding to a portion of human eIF2α (eukaryotic initiation factor-2α) phosphorylated at Ser51(Ser52 in mouse).
UniProt ID:P05198
Species reactivity:Human, Mouse
Specificity:Recognizes human and yeast eIF2α phosphorylated at Ser51 and mouse eIF2α phosphorylated at Ser52.
Crossreactivity:Does not cross-react with the unphosphorylated form of eIF2α.
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Formulation:Liquid. In Dulbecco's PBS, pH 7.3, containing 1mg/ml BSA, 50% glycerol and 0.05% sodium azide.
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Shipping:Dry Ice
Long Term Storage:-80°C
Regulatory Status:RUO - Research Use Only
[pSer52]Eukaryotic Initiation factor 2 alpha polyclonal antibody WB
Mouse 3T3 cell extracts were blotted and incubated with anti-eIF2-α (pS52) antibody following (1) prior incubation in the presence of the peptide immunogen, (2) the nonphosphopeptide corresponding to the eIF2-α (pS51) phosphopeptide, (3) or no peptide. Only the phospho-peptide corresponding to the region surrounding serine 51 (serine 52 in mouse) blocks the antibody signal.
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[pSer52]Eukaryotic Initiation factor 2 alpha polyclonal antibody WB

Product Literature References

Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside: M.J. Virgolini, et al.; Biochim. Biophys. Acta Mol. Cell Res. 1866, 225 (2019), Abstract;

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