Online Purchasing Account You are logged on as Guest. Login Register a New Account Shopping cart (Empty)

[pSer⁵²]Eukaryotic Initiation factor 2 α polyclonal antibody



BML-SA405-0020	20 µl	179.00 USD

BML-SA405-0100	100 µl	660.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:	eIF2α

Host:	Rabbit

Immunogen:	Synthetic peptide corresponding to a portion of human eIF2α (eukaryotic initiation factor-2α) phosphorylated at Ser⁵¹(Ser⁵² in mouse).

UniProt ID:	P05198

Species reactivity:	Human, Mouse Yeast

Specificity:	Recognizes human and yeast eIF2α phosphorylated at Ser⁵¹ and mouse eIF2α phosphorylated at Ser⁵².

Crossreactivity:	Does not cross-react with the unphosphorylated form of eIF2α.

Applications:	WB

Recommended Dilutions/Conditions:	Western Blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Formulation:	Liquid. In Dulbecco's PBS, pH 7.3, containing 1mg/ml BSA, 50% glycerol and 0.05% sodium azide.

Handling:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.

Shipping:	Shipped on Dry Ice

Long Term Storage:	-80°C

Regulatory Status:	RUO - Research Use Only

[pSer52]Eukaryotic Initiation factor 2 alpha polyclonal antibody WB

Mouse 3T3 cell extracts were blotted and incubated with anti-eIF2-α (pS52) antibody following (1) prior incubation in the presence of the peptide immunogen, (2) the nonphosphopeptide corresponding to the eIF2-α (pS51) phosphopeptide, (3) or no peptide. Only the phospho-peptide corresponding to the region surrounding serine 51 (serine 52 in mouse) blocks the antibody signal.

Please mouse over

Product Literature References

Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside: M.J. Virgolini, et al.; Biochim. Biophys. Acta Mol. Cell Res. 1866, 225 (2019), Abstract;