Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

PARP-1 monoclonal antibody (C-2-10)

BML-SA250-0050 50 µl 387.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:Poly(ADP-ribose) polymerase-1
Immunogen:Purified calf thymus poly(ADP-ribose) polymerase (PARP).
UniProt ID:P18493
Source:Mouse ascites.
Species reactivity:Human, Mouse, Rat
Bovine, Hamster, Monkey
Specificity:Recognizes an epitope in the C-terminal part of the DNA binding domain of PARP.
Crossreactivity:Does not cross-react with chicken PARP.
Applications:ELISA, IHC, WB
Application Notes:Detects bands ~116kDa (intact PARP) and ~85kDa (apoptosis-induced cleavage fragment) by Western blot.
Formulation:Liquid. Mouse ascites containing 0.02% sodium azide.
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
PARP-1 monoclonal antibody (C-2-10) Western blot
Western blot analysis of whole cell extracts from (1) human HL60 leukemia cells (Prod. No. BML-SW101] and (2) HL60 cells induced to undergo apoptosis using etoposide (Prod. No. BML-SW102). The membrane was probed with C-2-10 mouse monoclonal antibody (Prod. No. BML-SA250) at 1:1000 dilution, secondary antibody was GAMAP (1:2000) and developed with BCIP/NBT. Arrows correspond to 116kDa and 85kDa.
Please mouse over
PARP-1 monoclonal antibody (C-2-10) Western blot

Product Literature References

The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism: F. Stuhldreier, et al.; Cell Death Dis. 13, 938 (2022), Abstract;
Differential data on the responsiveness of multiple cell types to cell death induced by non-thermal atmospheric pressure plasma-activated solutions: K. Eto, et al.; Data Brief 36, 106995 (2021), Abstract; Full Text
Two experts and a newbie: [18F]PARPi vs [18F]FTT vs [18F]FPyPARP - a comparison of PARP imaging agents: S. Stotz, et al.; Eur. J. Nucl. Med. Mol. Imaging 1007, 259 (2021), Abstract;
Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy: R. Shiloh, et al.; Nat. Commun. 9, 1759 (2018), Abstract; Full Text
Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex: D. Schlutermann, et al.; Urol. Oncol. 36, 160.e1 (2018), Abstract;
Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation: A. Hay-Koren, et al.; J. Intern. Med. 281, 458 (2017), Abstract;
Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane: A. Mokhlesi, et al.; J. Nat. Prod. 80, 2941 (2017), Abstract;
Ultraconserved long non-coding RNA uc.63 in breast cancer: A. Marini, et al.; Oncotarget 8, 35669 (2017), Abstract; Full Text
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma: R.D. Rasmussen, et al.; Mol. Oncol. 10, 751 (2016), Abstract; Full Text
Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation: M. Charni, et al.; Cell Death Differ. 23, 509 (2016), Application(s): Western Blot, Abstract;
FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression: X. Hu, et al.; Int. J. Oncol. 46, 2309 (2015), Application(s): Western Blot, Abstract; Full Text
Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells: K.D. Sullivan, et al.; Cell Cycle 14, 1771 (2015), Abstract; Full Text

Related Products

PARP-1 monoclonal antibody (C-2-10) (affinity purified) 

Purified from ascites., ELISA, ICC, WB | Print as PDF
BML-SA249-0050 50 µg 428.00 USD
Do you need bulk/larger quantities?

PARP polyclonal antibody 

Whole rabbit serum., ELISA, WB | Print as PDF
BML-SA253-0025 25 µl 170.00 USD
BML-SA253-0100 100 µl 414.00 USD
Do you need bulk/larger quantities?

HL60 Cell Extract (non-induced) 

Print as PDF
BML-SW101-0200 200 µl 56.00 USD
Do you need bulk/larger quantities?

Jurkat, (cell lysate) 

Human, WB | Print as PDF
ADI-LYC-JK100-F 200 µg 143.00 USD
Do you need bulk/larger quantities?

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
PARP Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Product Flyers
The PARP Family & ADP Ribosylation
The PARP Family & ADP Ribosylation
Download as PDF

All new literature pieces