Product Details
| Alternative Name: | PAR |
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| Clone: | not available |
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| Host: | Mouse |
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| Isotype: | IgG3 |
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| Immunogen: | Purified poly(ADP-ribose) polymer (chain length of 2-50 units). |
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| Species reactivity: | Species independent
|
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| Applications: | ELISA, ICC, IP, WB
|
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| Recommended Dilutions/Conditions: | Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Purified from mouse ascites. |
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| Formulation: | Liquid. In PBS containing 50% glycerol. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Silencing of PARP2 Blocks Autophagic Degradation: L. Janko, et al.; Cells
9, 380 (2020),
Abstract;
Full Text
PARP-1/2 Inhibitor Olaparib Prevents or Partially Reverts EMT Induced by TGF-β in NMuMG Cells: M. Schacke, et al.; Int. J. Mol. Sci.
20, 518 (2019),
Abstract;
Full Text
Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair: X. Kong, et al.; J. Cell Sci.
131, jcs219311 (2018),
Abstract;
PARP Inhibition Prevents Ethanol-Induced Neuroinflammatory Signaling and Neurodegeneration in Rat Adult-Age Brain Slice Cultures: N. Tajuddin, et al.; J. Pharmacol. Exp. Ther.
365, 117 (2018),
Abstract;
Full Text
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization: L. Mc Gurk, et al.; Mol. Cell
71, 703 (2018),
Abstract;
P-Glycoprotein Inhibition Sensitizes Human Breast Cancer Cells to Proteasome Inhibitors: R.R. Deshmukh, et al.; J. Cell. Biochem.
118, 1239 (2017),
Abstract;
Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model: L.I. Hughes, et al.; PeerJ
5, e3318 (2017),
Abstract;
Full Text
Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites: G.M. Saquilabon Cruz, et al.; Nucleic Acids Res.
44, e27 (2016),
Abstract;
Full Text
Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis: J. Yu, et al.; BMC Gastroenterol.
16, 81 (2016),
Application(s): Western blot analysis of PARP activation,
Abstract;
Full Text
Alcohol-induced One-carbon Metabolism Impairment Promotes Dysfunction of DNA Base Excision Repair in Adult Brain: A.K. Fowler, et al.; J. Biol. Chem.
21, 287 (2012),
Abstract;
Full Text
Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells: J.H. Kupper, et al.; J. Biol. Chem.
265, 18721 (1990),
Abstract;
Rapid assay of poly(ADP-ribose) glycohydrolase: L. Menard & G.G. Poirier; Biochem. Cell Biol.
65, 668 (1987),
Abstract;
Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures: H. Kawamitsu, et al.; Biochemistry
23, 3771 (1984),
Abstract;
