Stable analog of PGF2α. Agonist at FP receptors (after in vivo hydrolysis to the free acid). It is an efficacious treatment for glaucoma. It also displays an unusual eye lash lengthening effect.
Product Details
| Alternative Name: | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide |
| |
| Formula: | C25H37NO4 |
| |
| MW: | 415.6 |
| |
| CAS: | 155206-00-1 |
| |
| Purity: | ≥97% |
| |
| Appearance: | White to off-white powder. |
| |
| Solubility: | Soluble in DMSO (25mg/ml) or ethanol (25mg/ml). |
| |
| Shipping: | Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
A meta-analysis of topical prostaglandin analogs in the treatment of chronic angle-closure glaucoma: J.W. Cheng, et al.; J. Glaucoma
18, 652 (2009),
Abstract;
Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides: S.D. Smid; Clin. Ophthalmol.
3, 663 (2009),
Abstract;
