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Bimatoprost

FP receptor agonist
 
BML-RA121-0001 1 mg 67.00 USD
 
BML-RA121-0010 10 mg 454.00 USD
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Stable analog of PGF2α. Agonist at FP receptors (after in vivo hydrolysis to the free acid). It is an efficacious treatment for glaucoma. It also displays an unusual eye lash lengthening effect.

Product Specification

Alternative Name:(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
 
Formula:C25H37NO4
 
MW:415.6
 
CAS:155206-00-1
 
Purity:≥97%
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

A meta-analysis of topical prostaglandin analogs in the treatment of chronic angle-closure glaucoma: J.W. Cheng, et al.; J. Glaucoma 18, 652 (2009), Abstract;
Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides: S.D. Smid; Clin. Ophthalmol. 3, 663 (2009), Abstract;

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