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Proteasome 20S α3 subunit monoclonal antibody (MCP257)

 
BML-PW8115-0025 25 µl 147.00 USD
 
BML-PW8115-0100 100 µl 478.00 USD
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Product Details

Alternative Name:Proteasome subunit α type-4, Macropain subunit C9, Proteasome subunit L
 
Clone:MCP257
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Human placenta derived proteasomes.
 
UniProt ID:P25789
 
Gene/Protein Identifier:PSMA4 (gene name)
 
Source:Purified from hybridoma tissue culture supernatant.
 
Species reactivity:Human, Mouse, Rat
Rabbit
 
Specificity:Recognizes the α3 subunit of the 20S proteasome.
 
Applications:IHC, WB
 
Purity Detail:Partially purified ascites.
 
Formulation:Liquid. In PBS containing 10mM sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from "standard" nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro: S.K. Shin, et al.; Exp. Mol. Med. 49, e287 (2017), Abstract; Full Text
Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis: F. Cerruti, et al.; Sci. Rep. 7, 17626 (2017), Abstract; Full Text
Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation: W.H. Choi, et al.; Nat. Commun. 7, 10963 (2016), Application(s): Western blot, Abstract;

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Proteasome 20S (alpha subunits) antibody sampler pack 

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