RWJ-60475-(AM)3 is a cell-permeable acetoxymethyl (AM) ester of RWJ-60475. The AM esters confer cell membrane permeability and are hydrolyzed by intracellular esterases, trapping the active inhibitor within the cell. The IC50 for the hydrolyzed, active inhibitor is 2 µM.
Product Details
| Formula: | C22H23BrNO13P |
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| MW: | 620.4 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Pale yellow-brown oil. |
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| Solubility: | Soluble in DMSO (25 mg/ml), acetone, or dimethylchloride. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Make solutions fresh daily. |
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| Handling: | Protect from moisture. |
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| Regulatory Status: | RUO - Research Use Only |
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