Replaces Prod. #: ALX-270-062
Potent and selective inhibitor of PP2A, IC50=53nM (IC50 for PP1=562nM). Useful for inhibiting PP1 and PP2A during purification of phosphorylated proteins.
Product Details
| Formula: | C10H14O5 |
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| MW: | 214.2 |
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| CAS: | 28874-45-5 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White solid. |
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| MeltingPoint: | 216-218°C |
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| Solubility: | Soluble in DMSO (25mg/ml) or ethanol (10mg/ml warm). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store, as supplied, at room temperature for up to 5 years. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation: R.R. Racine, et al.; Biochem. Biophys. Rep.
6, 172 (2016),
Application(s): Western blot and proliferation experiments,
Abstract;
Full Text
Protein phosphatase 2A and its [3H]cantharidin/[3H]endothall thioanhydride binding site. Inhibitor specificity of cantharidin and ATP analogues: Y.M. Li, et al.; Biochem. Pharmacol.
46, 1435 (1993),
Abstract;
Cantharidin-binding protein: identification as protein phosphatase 2A: Y.M. Li & J.E. Casida; PNAS
89, 11867 (1992),
Abstract;
