Argatroban is a synthetic peptidomimetic thrombin inhibitor which is in clinical use. It presents significant advantages as an anticoagulant in deep vein thrombosis, stroke prevention in atrial fibrillation and thromboembolic disease and especially in patients with coronary artery disease and heparin-induced thrombocytopenia.
Product Details
| Formula: | C23H36N6O5S |
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| MW: | 508.6 |
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| CAS: | 74863-84-6 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Determined by NMR and LCMS. |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Nafamostat mesilate improves function recovery after stroke by inhibiting neuroinflammation in rats: C. Li, et al.; Brain Behav. Immun.
56, 230 (2016),
Application(s): Positive control,
Abstract;
Nafamostat mesilate protects against acute cerebral ischemia via blood-brain barrier protection: J. Want, et al.; Neuropharmacology
105, 398 (2016),
Application(s): Administered intravenously into rats,
Abstract;
Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice: X. de la Rosa, et al.; Stroke
45, 1453 (2014),
Application(s): Used in osmotic pump with rat brain samples,
Abstract;
