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Gabexate . mesylate

Protease inhibitor
BML-PI144-0010 10 mg 84.00 USD
BML-PI144-0050 50 mg 333.00 USD
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A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.

Product Specification

Formula:C16H23N3O4 . CH3SO3H
Purity:≥98% (HPLC)
Appearance:White solid.
Solubility:Soluble in water (25 mg/ml).
Long Term Storage:-20°C
BML-PI144 structure
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BML-PI144 structure

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