A structurally unique activator of PKC in whole cells or in purified enzyme preparations (Kd=2.5 µM) which is equipotent with dioleoylglycerol. Since it does not possess hydrolyzable esters of fatty acids, it represents a stable, persistent PKC activator.
Product Details
| Alternative Name: | FTT |
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| Formula: | C17H26N3S |
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| MW: | 305.5 |
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| CAS: | 156604-45-4 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Yellow oil. |
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| Solubility: | Soluble in DMSO or 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions under an inert atmosphere at -20°C for up to 3 months. |
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| Handling: | Protect from air. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Farnesyl thiotriazole, a potent neutrophil agonist and structurally novel activator of protein kinase C: B.A. Gilbert, et al.; Biochemistry
34, 3916 (1995),
Abstract;
