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4α-Phorbol 12-myristate 13-acetate

PKC activator
 
BML-PE162-0001 1 mg 88.00 USD
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Replaces Prod. #: ALX-445-005

Negative control for phorbol 12-myristate 13-acetate (PMA) (Prod. No. BML-PE160).

Product Details

Alternative Name:4-α-PMA, 4-α-TPA
 
Formula:C36H56O8
 
MW:616.8
 
CAS:63597-44-4
 
Purity:≥99% (HPLC, TLC)
 
Appearance:Off-white to yellow powder.
 
Solubility:Soluble in DMSO (25mg/ml), methanol, 100% ethanol or ethyl acetate.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
445-005
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445-005

Product Literature References

Alpha defensin-1 attenuates surgically induced osteoarthritis in association with promoting M1 to M2 macrophage polarization: J.W. Xie, et al.; Osteoarthritis Cartilage 29, 1048 (2021), Abstract;
Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay: L. Saraiva, et al.; Eur. J. Pharmacol. 491, 101 (2004), Abstract;
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin: B.L. Van Duuren, et al.; Cancer Res. 39, 2644 (1979), Abstract;

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