Replaces Prod. #: ALX-445-005
Negative control for phorbol 12-myristate 13-acetate (PMA) (Prod. No. BML-PE160).
Product Details
| Alternative Name: | 4-α-PMA, 4-α-TPA |
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| Formula: | C36H56O8 |
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| MW: | 616.8 |
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| CAS: | 63597-44-4 |
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| Purity: | ≥99% (HPLC, TLC) |
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| Appearance: | Off-white to yellow powder. |
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| Solubility: | Soluble in DMSO (25mg/ml), methanol, 100% ethanol or ethyl acetate. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Alpha defensin-1 attenuates surgically induced osteoarthritis in association with promoting M1 to M2 macrophage polarization: J.W. Xie, et al.; Osteoarthritis Cartilage
29, 1048 (2021),
Abstract;
Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay: L. Saraiva, et al.; Eur. J. Pharmacol.
491, 101 (2004),
Abstract;
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin: B.L. Van Duuren, et al.; Cancer Res.
39, 2644 (1979),
Abstract;
