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PDE inhibitor
BML-PD129-0010 10 mg 79.00 USD
BML-PD129-0050 50 mg 323.00 USD
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Phosphodiesterase PDE II inhibitor, IC50=0.8 µM. Also inhibits adenosine deaminase, Ki=4 nM.

Product Details

Alternative Name:Erythro-9-(2-hydroxy-3-nonyl)adenine . HCl
Formula:C14H23N5O . HCl
Purity:≥98% (HPLC)
Appearance:White solid.
Solubility:Soluble in water (25mg/ml).
Shipping:Ambient Temperature
Long Term Storage:Ambient
Regulatory Status:RUO - Research Use Only
BML-PD129 structure
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BML-PD129 structure

Product Literature References

Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes: P.F. Mery, et al.; Mol. Pharmacol. 48, 121 (1995), Abstract;
Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine: T. Podzuweit, et al.; Cell. Signal. 7, 733 (1995), Abstract;
Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition: M. Bessodes, et al.; Biochem. Pharmacol. 31, 879 (1982), Abstract;