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Substrate for ubiquitin C-terminal hydrolases (UCHs)
BML-P801-0005 5 mg 253.00 USD
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Fluorogenic substrate for ubiquitin C-terminal hydrolases (UCHs), including UCH-L3 and Isopeptidase T. Sequence is based on the C-terminal residues of ubiquitin. Ex.: 380 nm Em.: 460 nm.

Product Details

Alternative Name:Z-LRGG-AMC, Ubiquitin C-terminal hydrolase substrate (fluorogenic), UCH substrate (fluorogenic)
Sequence:Z-Leu-Arg-Gly-Gly-AMC (7-amino-4-methylcoumarin)
Appearance:Lyophilized solid.
Solubility:Soluble in DMSO.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells: M. Oroń, et al.; Cell Rep. 40, 111428 (2022), Abstract;
Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome: K.V. Ramachandran, et al.; Mol. Cell 71, 169 (2018), Abstract; Full Text

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