Sequence is from hamster polyoma virus middle T inclusive of Tyr324. This 11-residue phosphopeptide activates Src family members by binding with high affinity (Kd=3-6 nM for Src SH2) to their SH2 domains. The crystal structures of this peptide complexed to Src and Lck SH2 domains have been determined.
Product Details
| Sequence: | Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu |
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| MW: | 1473.7 |
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| Purity: | ≥98% |
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| Appearance: | Lyophilized solid. |
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| Solubility: | Soluble in Water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Tyrosine Phosphorylation Determines Afterdischarge Initiation by Regulating an Ionotropic Cholinergic Receptor: S.H. White, et al.; Neuroscience
372, 273 (2018),
Abstract;
