Heat-stable protein kinase inhibitor (PKI) peptide sequence (14-22). N-terminus is myristoylated to increase cell membrane permeability. The non-myristoylated version of this peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA) with Ki=36 nM. This product is a useful tool for studying PKA in cellular systems.
Product Details
| Alternative Name: | cAMP-dependent protein kinase inhibitor (14-22) amide (myristoylated) |
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| Sequence: | N-myristoyl-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2 |
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| Formula: | C53H100N20O12 |
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| MW: | 1209.5 |
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| Source: | Synthetic. |
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| CAS: | 201422-03-9 |
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| Formulation: | Lyophilized. Trifluoroacetate salt. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Solid. |
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| Solubility: | Soluble to at least 1mg/ml in water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from moisture. |
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| Technical Info/Product Notes: | Replacement for ADI-HPK-108 |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Abstract;
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Abstract;
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