Fluorogenic substrate for dipeptidyl peptidase IV (DPIV, DPPIV, CD26) (kcat/Km=2.6 x 105s-1M-1), DPPII/VII, DPP8 and DPP9, FAP (fibroblast activation protein), and likely POP/PREP, but not glutamate carboxypeptidase II. Can be used in vitro, for inhibitor screening, and in biological fluids. Ex = 380 nm, Em=460 nm.
Product Specification
| Alternative Name: | Gly-Pro-AMC, Dipeptidyl peptidase substrate (fluorogenic) |
| |
| Sequence: | H-Gly-Pro-7-amino-4-methylcoumarin |
| |
| MW: | 410.3 |
| |
| CAS: | 115035-46-6 |
| |
| Purity: | ≥97% |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Design and synthesis of aminocoumarin derivatives as DPP-IV inhibitors and anticancer agents: R. Soni, et al.; Bioorg. Chem.
79, 277 (2018),
Abstract;
