Fluorogenic substrate for dipeptidyl peptidase IV (DPIV, DPPIV, CD26) (kcat/Km=2.6 x 105s-1M-1), DPPII/VII, DPP8 and DPP9, FAP (fibroblast activation protein), and likely POP/PREP, but not glutamate carboxypeptidase II. Can be used in vitro, for inhibitor screening, and in biological fluids. Ex = 380 nm, Em=460 nm.
Product Details
| Alternative Name: | Gly-Pro-AMC, Dipeptidyl peptidase substrate (fluorogenic) |
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| Sequence: | H-Gly-Pro-7-amino-4-methylcoumarin |
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| MW: | 410.3 |
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| CAS: | 115035-46-6 |
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| Purity: | ≥97% |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Design and synthesis of aminocoumarin derivatives as DPP-IV inhibitors and anticancer agents: R. Soni, et al.; Bioorg. Chem.
79, 277 (2018),
Abstract;
