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GP-AMC

DPP substrate
 
BML-P189-0005 5 mg 95.00 USD
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Fluorogenic substrate for dipeptidyl peptidase IV (DPIV, DPPIV, CD26) (kcat/Km=2.6 x 105s-1M-1), DPPII/VII, DPP8 and DPP9, FAP (fibroblast activation protein), and likely POP/PREP, but not glutamate carboxypeptidase II. Can be used in vitro, for inhibitor screening, and in biological fluids. Ex = 380 nm, Em=460 nm.

Product Specification

Alternative Name:Gly-Pro-AMC, Dipeptidyl peptidase substrate (fluorogenic)
 
Sequence:H-Gly-Pro-7-amino-4-methylcoumarin
 
MW:410.3
 
CAS:115035-46-6
 
Purity:≥97%
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

Design and synthesis of aminocoumarin derivatives as DPP-IV inhibitors and anticancer agents: R. Soni, et al.; Bioorg. Chem. 79, 277 (2018), Abstract;

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