Fluorogenic substrate specific for cathepsin K, among other cathepsin family members. This substrate is also cleaved by granzyme A, thrombin, tryptase, trypsin, and kallikreins. Ex.: 365 nm, Em.: 440 nm, although the following Ex/Em can also be used: 355,380/450,460. This substrate is useful for inhibitor screening and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144).
Product Details
| Alternative Name: | Z-Gly-Pro-Arg-AMC |
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| Sequence: | Z-Gly-Pro-Arg-AMC . HCl [Z=Cbz=Benzyloxycarbonyl; AMC=7-amino-4-methylcoumarin] |
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| MW: | 656.1 |
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| Formulation: | C31H37N7O7 |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | White powder. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Abstract;
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Full Text
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Full Text
