Chromogenic substrate specific for cathepsin B. Release of pNA in monitored at 405-410 nm. This substrate is useful for inhibitor screening and kinetic analysis. Also available: calibration standard pNA (BML-KI145).
Product Details
| Alternative Name: | Z-Arg-Arg-pNA |
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| Sequence: | Z-Arg-Arg-pNA . 2HCl [Z=Cbz=Benzyloxycarbonyl; pNA=p-nitroanilide] |
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| Formula: | C26H36N10O6 . 2HCl |
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| MW: | 657.6 |
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| CAS: | 201807-90-1 |
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| Purity: | ≥99% |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Cell penetrable, clickable and tagless activity-based probe of human cathepsin L: D. Dana, et al.; Bioorg. Chem.
85, 505 (2019),
Application(s): Activity assay,
Abstract;
Development of a highly potent, selective, and cell-active Inhibitor of cysteine cathepsin L-A hybrid design approach: D. Dana, et al.; Chem. Commun. (Camb.)
50, 10875 (2014),
Abstract;
