Replaces Prod. #: ALX-151-023
Sequence, KKALRRQETVDAL, derived from Ca2+/calmodulin-dependent protein kinase II autophosphorylation site RQETVD plus basic residues to facilitate phosphocellulose binding. Contains consensus phosphorylation sequence R-X-X-S/T. Highly selective CaMKII substrate (Km=2 µM for CaMKII; 50 µM for PKC; no activity towards PKA).
Product Details
| Sequence: | H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH |
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| Formula: | C65H118N22O20 |
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| MW: | 1527.8 |
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| Source: | Synthetic. |
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| Formulation: | Lyophilized. |
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| Purity: | ≥95% (HPLC) |
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| Identity: | Determined by MS. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation: P.I. Hanson, et al.; Neuron
3, 59 (1989),
Abstract;
