Potent and selective serotonin uptake inhibitor. Clinically useful antidepressant.
Product Details
Formula: | C17H18F3NO . HCl |
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MW: | 345.8 |
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CAS: | 56296-78-7 |
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Purity: | ≥98% (UHPLC) |
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Appearance: | White crystalline powder. |
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Solubility: | Soluble in water (4mg/ml). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac): Y.G. Ni & R. Miledi; Proc. Natl. Acad. Sci. USA
94, 2036 (1997),
Abstract;
Full Text
Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication: D.T. Wong, et al.; Life Sci.
57, 411 (1995),
Abstract;
The interaction of antidepressant drugs with central and peripheral (enteric) 5-HT3 and 5-HT4 receptors: A. Lucchelli, et al.; Br. J. Pharmacol.
114, 1017 (1995),
Abstract;
Full Text
Binding of antidepressants to human brain receptors: focus on newer generation compounds: B. Cusack, et al.; Psychopharmacology (Berlin)
114, 559 (1994),
Abstract;
Facilitation of 5-hydroxytryptamine3 receptor desensitization by fluoxetine: P. Fan, et al.; Neuroscience
62, 515 (1994),
Abstract;