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Bradykinin receptor ligand
BML-NK104-0001 1 mg 321.00 USD
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A potent and selective bradykinin B2 antagonist. HOE-140 is a useful tool for discrimination of the physiological roles of bradykinin B2 versus B1 receptors. Displays a protective effect in myocardial reperfusion injury.

Product Details

Alternative Name:Icatibant
Purity:≥95% (HPLC)
Identity:Determined by MS.
Appearance:White solid.
Solubility:Soluble in water.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment: A. Nokkari, et al.; PLoS One 10, e0128601 (2015), Application(s): Cell Culture, Abstract; Full Text
BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2: A. Tiritilli, et al.; Methods Find. Exp. Clin. Pharmacol. 26, 247 (2004), Abstract;
Bradykinin regulates cyclooxygenase-2 in rat renal thick ascending limb cells: J. A. Rodriguez, et al.; Hypertension 44, 230 (2004), Abstract; Full Text
Correlation between brain bradykinin receptor binding sites and cardiovascular function in young and adult spontaneously hypertensive rats: F. Cloutier, et al.; Br. J. Pharmacol. 142, 285 (2004), Abstract; Full Text
Protective effect of bradykinin antagonist Hoe-140 during in vivo myocardial ischemic-reperfusion injury in the cat: R. Kumari, et al.; Regul. Pept. 115, 211 (2003), Abstract;

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