Replaces Prod. #: ALX-550-235
Derivative of amiloride (Prod. No. BML-CA200). Potent sodium channel blocker.
Product Details
| Alternative Name: | Benzylamiloride . HCl, N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide . HCl |
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| Formula: | C13H14ClN7O . HCl |
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| MW: | 356.2 |
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| CAS: | 161804-20-2 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Yellow solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Regulation of brain renin-angiotensin system by benzamil-blockable sodium channels: M. Nishimura, et al.; Am. J. Physiol.
276, R1416 (1999),
Abstract;
Modulation of cardiac performance by amiloride and several selected derivatives of amiloride: G.N. Pierce, et al.; J. Pharmacol. Exp. Ther.
265, 1280 (1993),
Abstract;
Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes: J.W. Lane, et al.; Br. J. Pharmacol.
106, 283 (1992),
Abstract;
Amiloride and its analogs as tools in the study of ion transport: T.R. Kleyman & E.J. Cragoe; J. Membr. Biol.
105, 1 (1988),
Abstract;
