A previously undescribed human testicular olfactory receptor known as hOR17-4 was cloned and functionally expressed. Bourgeonal is a potent agonist at hOR17-4 and acts as a strong chemoattractant in sperm behavioral assays. The bourgeonal, hOR17-4 signaling pathway potentially governs chemical communication between sperm and egg and may be used to manipulate or block fertilization.
Product Details
| Alternative Name: | 4-t-Butylbenzenepropionaldehyde |
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| Formula: | C13H18O |
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| MW: | 190.3 |
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| CAS: | 18127-01-0 |
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| Purity: | ≥90% (TLC) |
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| Appearance: | Colorless oil. |
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| Solubility: | Soluble in DMSO (25 mg/ml)or ethanol (25 mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Novel function of beta-arrestin2 in the nucleus of mature spermatozoa: E. M. Neuhaus, et al.; J. Cell Sci.
119, 3047 (2006),
Abstract;
Full Text
Identification of a testicular odorant receptor mediating human sperm chemotaxis: M. Spehr, et al.; Science
299, 2054 (2003),
Abstract;
