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L-NASPA

LPA receptor ligand
 
BML-LP101-0001 1 mg 107.00 USD
 
BML-LP101-0005 5 mg 347.00 USD
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L-NASPA is an antagonist of LPA-induced platelet aggregation and chloride conductance in Xenopus oocytes. In human breast carcinoma MDA-MB231 cells it is a potent LPA agonist.

Product Specification

Alternative Name:N-Palmitoyl-L-serine phosphoric acid
 
Formula:C19H38NO7P . H2O
 
MW:440.5
 
CAS:155915-46-1
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO (10 mg/ml)or ethanol (10 mg/ml).
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Store, as supplied, at -80°C for up to 1 year. Store solutions at -20°C for up to 1 year.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Characterization of a receptor subtype-selective lysophosphatidic acid mimetic: S. B. Hooks, et al.; Mol. Pharmacol. 53, 188 (1998), Abstract; Full Text
N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors: K. Liliom, et al.; Mol. Pharmacol. 50, 616 (1996), Abstract;
Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: comparison with platelet activating factor: T. Sugiura, et al.; Arch. Biochem. Biophys. 311, 358 (1994), Abstract;

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