K+ channel blocker. Blocks Kv1.2 and Kv1.1 channels (IC50=0.13 and 3.1nM in oocytes respectively, with higher values for mammalian cells), as well as heteromultimeric channels comprised of Kv1.2 and Kv1.1 with other Kv1 isoforms.
Product Details
| MW: | 7149 |
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| CAS: | 107950-33-4 |
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| UniProt ID: | P00979 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥98% (HPLC) |
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| Solubility: | Soluble in aqueous buffers (pH 7.5). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
Dendrotoxin poisoning in a neurobiochemist: S.W. Munday, et al.; J. Toxicol. Clin. Toxicol.
41, 163 (2003),
Abstract;
