Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Penitrem A

K+ channel blocker
BML-KC157-0001 1 mg 74.00 USD
BML-KC157-0005 5 mg 206.00 USD
Do you need bulk/larger quantities?
Replaces Prod. #: ALX-630-020

Fungal mycotoxin. Selective, irreversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (100% block at 10 nM). Increases spontaneous release of GABA and aspartate from cerebrocortical synaptosomes in rat neuromuscular junction.

Product Details

Alternative Name:NSC 354845, Tremortin A
Purity:≥95% (HPLC, TLC)
Appearance:White solid.
Solubility:Soluble in organic solvents such as methanol, acetone or DMSO.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
BML-KC157 structure
Please mouse over
BML-KC157 structure

Product Literature References

Chlorinated flavonoids modulate the inflammatory process in human blood: C. Proença, et al.; Inflammation. 40, 1155 (2017), Abstract;
The cyclooctadepsipeptide anthelmintic emodepside differentially modulates nematode, insect and human calcium-activated potassium (SLO) channel alpha subunits: A. Crisford, et al.; PLoS Negl. Trop. Dis. 9, e0004062 (2015), Abstract; Full Text
Brain neurotoxicity of Penitrem A: electrophysiological, behavioral and histopathological study: P. Breton, et al.; Toxicon 36, 645 (1998), Abstract;
Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels: H.G. Knaus, et al.; Biochemistry 33, 5819 (1994), Abstract;
Effects of a fungus tremorgenic toxin (penitrem A) on transmission in rat phrenic nerve-diaphragm preparations: B.J. Wilson, et al.; Brain Res. 40, 540 (1972), Abstract;

Related Literature

Download as PDF

All new literature pieces