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20-Hydroxy-leukotriene B4

 
BML-HLB004-0050 50 µg 392.00 USD
 
BML-HLB004-1000 1 mg 4,057.00 USD
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Primary LTB4 metabolite produced by ω oxidation in PMNL retaining some chemotactic activity. ω oxidation is blocked by 17-ODYA.

Product Specification

Alternative Name:20-Hydroxy-LTB4
 
Formula:C20H32O5
 
MW:352.5
 
Source:Synthetic.
 
CAS:79516-82-8
 
Concentration:50 µg/ml
 
Formulation:Solution in ethanol.
 
Purity:≥99% (HPLC)
 
Appearance:Clear to light-yellow liquid.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Identification and functional characterization of leukotriene B4 20-hydroxylase of human polymorphonuclear leukocytes: R. J. Soberman, et al.; Proc. Natl. Acad. Sci. USA 82, 2292 (1985), Abstract; Full Text
Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes: S. Shak, et al.; J. Biol. Chem. 259, 10181 (1984), Abstract; Full Text
Properties of leukotriene B4 20-hydroxylase from polymorphonuclear leukocytes: W. S. Powell, et al.; J. Biol. Chem. 259, 3082 (1984), Abstract; Full Text
Stereospecificity of leukotriene B4 and structure-function relationships for chemotaxis of human neutrophils: C. A. Dahinden, et al.; J. Immunol. 133, 1477 (1984), Abstract;

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