Biosynthesis by platelet 12-lipoxygenase. Chemotactic and chemokinetic for PMNL2 and for vascular smooth muscle cells. Antiproliferative effect on smooth muscle cells. Second messenger in angiotensin induced aldosterone production. Induces endothelial cell retraction and tumor cell adhesion.
Product Details
Alternative Name: | 12(S)-HETE |
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Formula: | C20H32O3 |
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MW: | 320.5 |
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CAS: | 54397-83-0 |
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Concentration: | 50 µg/ml |
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Formulation: | Liquid. Solution in ethanol. |
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Purity: | ≥98% (HPLC) |
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Appearance: | Liquid. |
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Shipping: | Shipped on Dry Ice |
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Long Term Storage: | -80°C |
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Regulatory Status: | RUO - Research Use Only |
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