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DIF-1

Ultra-pure; Induces cell differentiation
 
BML-GR324-0100 100 µg 81.00 USD
 
BML-GR324-0500 500 µg 330.00 USD
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Supresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60 cells. It is a known inhibitor of Wnt/β-Catenin signaling pathway.

Product Details

Alternative Name:1-(3,5-Dichloro-2,6-dihydroxy-4-methoxyphenyl) hexan-1-one, Differentiation-inducing factor-1
 
Formula:C13H16Cl2O4
 
MW:307.2
 
CAS:111050-72-7
 
Purity:≥98% (HPLC)
 
Appearance:Pale yellow solid.
 
Solubility:Soluble in ethanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Evolution of a novel cell type in Dictyostelia required gene duplication of a cudA-like transcription factor: K. Kin, et al.; Curr. Biol. S0960 (2021), Abstract;
Autophagy dysfunction and ubiquitin-positive protein aggregates in Dictyostelium cells lacking Vmp1: J. Calvo-Garrido & R. Escalante; Autophagy 6, 99 (2010), Abstract;
DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60: Y. Kubohara, et al.; Biochem. Biophys. Res. Commun. 236, 418 (1997), Abstract;

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