Supresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60 cells. It is a known inhibitor of Wnt/β-Catenin signaling pathway.
Product Details
Alternative Name: | 1-(3,5-Dichloro-2,6-dihydroxy-4-methoxyphenyl) hexan-1-one, Differentiation-inducing factor-1 |
|
Formula: | C13H16Cl2O4 |
|
MW: | 307.2 |
|
CAS: | 111050-72-7 |
|
Purity: | ≥98% (HPLC) |
|
Appearance: | Pale yellow solid. |
|
Solubility: | Soluble in ethanol. |
|
Shipping: | Shipped on Blue Ice |
|
Long Term Storage: | -20°C |
|
Regulatory Status: | RUO - Research Use Only |
|
Please mouse over
Product Literature References
Evolution of a novel cell type in Dictyostelia required gene duplication of a cudA-like transcription factor: K. Kin, et al.; Curr. Biol. S0960 (2021),
Abstract;
Autophagy dysfunction and ubiquitin-positive protein aggregates in Dictyostelium cells lacking Vmp1: J. Calvo-Garrido & R. Escalante; Autophagy
6, 99 (2010),
Abstract;
DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60: Y. Kubohara, et al.; Biochem. Biophys. Res. Commun.
236, 418 (1997),
Abstract;