Replaces Prod. #: ALX-380-042
A broad spectrum antitumor agent. Induces DNA damage by intercalating into DNA and inhibiting topoisomerase II. Binds covalently to DNA. Inhbibits reverse transcriptase, RNA polymerase and the catalytic activity of Dnmt1. Immunosuppressive. Antineoplastic. Induces apoptosis. Down regulates c-myc and c-jun in doxorubicin-sensitive cells.
Product Details
| Alternative Name: | DXR . HCl, 14-Hydroxydaunomycin . HCl, Adriamycin . HCl |
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| Formula: | C27H29NO11 . HCl |
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| MW: | 580.0 |
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| CAS: | 25316-40-9 |
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| MI: | 14: 3439 |
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| RTECS: | QI9295900 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Red solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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