Acitretin is a synthetic aromatic analog of all trans retinoic acid with increased stability in vivo. It is the active free acid form of the antipsoriatic drug etretinate. Displays antiproliferative effect and induces apoptosis in Kaposi's sarcoma cells.
Product Details
| Formula: | C21H26O3 |
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| MW: | 326.4 |
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| CAS: | 55079-83-9 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Yellow solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A review of acitretin, a systemic retinoid for the treatment of psoriasis: C.S. Lee & J. Koo; Expert Opin. Pharmacother.
6, 1725 (2005),
Abstract;
Retinoids: therapeutic applications and mechanisms of action in cutaneous T-cell lymphoma: C. Zhang & M. Duvic ; Dermatol. Ther.
16, 322 (2003),
Abstract;
Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells: J. Corbeil, et al.; J. Clin. Invest.
93, 1981 (1994),
Abstract;
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