Glucagon-like peptide 2 is a 33- or 34-amino acid peptide located at the C-terminus of, and cleaved from, pro-glucagon by prohormone convertase 3 (PC3). GLP-2 is a potent intestinotropic growth factor, the action of which is transduced by G protein-coupled membrane-bound receptors (GLP2-R) found in the gut. GLP-2Rs are also found in the rodent CNS. The main actions of GLP-2 appear to be crypt cell proliferation, inhibition of enterocyte apoptosis, enhancement of nutrient adsorption and certain reparative effects. Applications: antiserum adsorption control; standard or tracer for immunoassay.
Product Details
| Alternative Name: | GLP 2 |
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| Sequence: | H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH |
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| MW: | 3922.4 |
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| CAS: | 99120-49-7 |
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| Purity: | ≥90% |
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| Appearance: | Lyophilized solid. |
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| Solubility: | Soluble in dilute acetic acid at 1mg/mL. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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