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Glucagon like peptide 1 (human) (7-36) amide

 
BML-GP1438-0100 100 µg 161.00 USD
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A predominant cleaved form of pro-glucagon expressed in the intestine. GLP-1 [7-36]amide is promptly released from the gut after oral ingestion of a meal where it slows gastric emptying and exerts a powerful insulinotropic action leading to elevated serum insulin levels. GLP-1 [7-36] amide promotes satiety and reduces food intake in patients with diabetes mellitus type 2 and has been suggested to have therapeutic potential in the treatment of NIDDM. It has been reported that human pancreatic endocrine tumors contain molecular forms of GLP-1 which resemble those expressed in the small intestine, rather than in their tissue of origin.

Product Specification

Alternative Name:GLP 1 (7-36) amide
 
Sequence:H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
 
MW:3297.7
 
Appearance:Lyophilized solid.
 
Solubility:Soluble in water at 1mg/mL.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

GLP-1 Mediated Diuresis and Natriuresis Are Blunted in Heart Failure and Restored by Selective Afferent Renal Denervation: K. Katsurada, et al.; Cardiovasc. Diabetol. 19, 57 (2020), Abstract; Full Text

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