Control peptide for Anti-Glucagon-like Peptide 1 (BML-GA1176). Blocks immunoreactivity at 10nmol per mL diluted antibody.
Product Specification
| Alternative Name: | GLP 1 (1-19), pro-Glucagon (92-110), Blocking peptide for Glucagon like peptide 1 pAb (Prod. No. BML-GA1176) |
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| Sequence: | H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-OH |
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| Formula: | C95H132N26O36 |
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| MW: | 2214.1 |
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| Formulation: | Lyophilized. Trifluoroacetate salt. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Solid. |
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| Solubility: | Soluble in water at 1mg/mL. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable as supplied for at least 24 months at -20°C in the dark. Storage of solutions is not recommended. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans: E. Naslund, et al.; Am. J. Physiol.
277, R910 (1999),
Abstract;
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2: J. P. Gutzwiller, et al.; Am. J. Physiol.
276, R1541 (1999),
Abstract;
Glucagon-like peptides: D. J. Drucker, et al.; Diabetes
47, 159 (1998),
Abstract;
A role for glucagon-like peptide-1 (GLP-1) in the central regulation of feeding: M. D. Turton, et al.; Nature
379, 69 (1996),
Abstract;
Glucagon-like peptide-1 (GLP-1) molecular forms in human pancreatic endocrine tumours resemble those in intestine rather
than pancreas: K. Tateishi, et al.; Diabetes Res. Clin. Pract.
25, 43 (1994),
Abstract;
The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1[7-37] in normal and diabetic subjects: D. Elahi, et al.; Regul. Peptides
51, 53 (1994),
Abstract;
Exendin-4 is a high potency agonist and truncated exendin[9-39]amide is an antagonist at the glucagon-like peptide-1[7-36]amide receptor of insulin-secreting beta-cells: R. Goke, et al.; J. Biol. Chem.
268, 19650 (1993),
Abstract;
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