This is the active carboxylate form of mevastatin. It is active in whole cells as well as in cell free assays.
Product Details
| Formula: | C23H35O6. Na |
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| MW: | 430.5 |
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| CAS: | 99782-89-5 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| MeltingPoint: | 44-45°C |
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| Solubility: | Soluble in ethanol (20 mg/ml) and DMSO (30 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The discovery and development of HMG-CoA reductase inhibitors: A. Endo, et al.; J. Lipid Res.
33, 1569 (1992),
Abstract;
Full Text
Essential role for mevalonate synthesis in DNA replication: V. Quesney-Huneeus, et al.; Proc. Natl. Acad. Sci. USA
76, 5056 (1979),
Abstract;
Full Text
