4-Oxatetradecanoic acid is a myristate analog which has similar chain length but reduced hydrophobicity compared to myristate. It inhibits replication of human immunodeficiency virus I and is fungicidal for Cryptococcus neoformans. Its specific mechanism of action is not clear but it is believed to either inhibit the activity of N-myristoyltransferase or modulate the function of target acylated proteins.
Product Details
| Formula: | C13H26O3 |
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| MW: | 230.3 |
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| Source: | Synthetic. |
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| CAS: | 7420-16-8 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Low melting white to off-white solid. |
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| Solubility: | Soluble in DMSO (25mg/ml) and ethanol (25mg/ml). |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I: C.A. Langner, et al.; J. Biol. Chem.
267, 17159 (1992),
Abstract;
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