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Geranylgeranylpyrophosphate . triammonium salt

BML-G225-0200 200 µg Inquire for pricing
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Replaces Prod. #: ALX-290-006

Geranylgeranylpyrophosphate is a geranylgeranyl-donor molecule which is utilized by geranylgeranyltransferase for isoprenylation of target proteins.

Product Details

Formula:C20H36O7P2 . 3NH3
MW:450.5 . 51.1
Formulation:Liquid. In isopropanol: NH4OH (7:3)
Solubility:Soluble in water; also soluble in methanol or 100% ethanol.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis: F. Ahsan, et al.; Sci. Rep. 8, 1520 (2018), Abstract; Full Text
Divalent cation and prenyl pyrophosphate specificities of the protein farnesyltransferase from rat brain, a zinc metalloenzyme: Y. Reiss, et al.; J. Biol. Chem. 267, 6403 (1992), Abstract;
Effects of tautomycin, a protein phosphatase inhibitor, on recycling of mammalian cell surface molecules: T. Kurisaki, et al.; J. Antibiot. 45, 252 (1992), Abstract;
Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys: M.C. Seabra, et al.; J. Biol. Chem. 267, 14497 (1992), Abstract;
Steady-state kinetic mechanism of Ras farnesyl:protein transferase: D.L. Pompliano, et al.; Biochemistry 31, 3800 (1992), Abstract;