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Farnesylthioacetic acid

Methyltransferase inhibitor
BML-G222-0005 5 mg 100.00 USD
BML-G222-0025 25 mg 387.00 USD
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Replaces Prod. #: ALX-290-004

FTA potently and specifically inhibits methyl esterification of farnesylated proteins such as the γ subunit of transducin (70% at 10µM). It does not act as a substrate for methyl transferase.

Product Details

Alternative Name:FTA
Purity:≥98% (TLC)
Appearance:Yellow viscous oil.
Solubility:Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).
Shipping:Ambient Temperature
Long Term Storage:-20°C
Use/Stability:Solutions are stable for up to 6 months when stored at -20°C.
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Activation of TRPA1 by farnesyl thiosalicylic acid: M. Maher, et al.; Mol. Pharmacol. 73, 1225 (2008), Abstract;
Identifying the recognition unit for G protein methylation: E.W. Tan, et al.; J. Biol. Chem. 266, 10719 (1991), Abstract;