Replaces Prod. #: ALX-290-004
FTA potently and specifically inhibits methyl esterification of farnesylated proteins such as the γ subunit of transducin (70% at 10µM). It does not act as a substrate for methyl transferase.
Product Details
| Alternative Name: | FTA |
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| Formula: | C17H28O2S |
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| MW: | 296.5 |
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| Source: | Synthetic. |
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| CAS: | 135784-48-4 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Yellow viscous oil. |
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| Solubility: | Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Solutions are stable for up to 6 months when stored at -20°C. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Activation of TRPA1 by farnesyl thiosalicylic acid: M. Maher, et al.; Mol. Pharmacol.
73, 1225 (2008),
Abstract;
Identifying the recognition unit for G protein methylation: E.W. Tan, et al.; J. Biol. Chem.
266, 10719 (1991),
Abstract;
