Idebenone is a quinone antioxidant chemically related to ubiquinone. It is a free radical scavenger that protects mitochondrial membranes from lipid peroxidation. It improves overall brain function in various animal models and protective effect on astrocytes is due in part via increased NGF production.
Product Details
| Alternative Name: | 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione |
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| Formula: | C19H30O5 |
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| MW: | 338.4 |
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| CAS: | 58186-27-9 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Orange solid. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Apoptosis modulators in the therapy of neurodegenerative diseases: H. P. Deigner, et al.; Expert Opin. Investig. Drugs
9, 747 (2000),
Abstract;
CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production: K. Takuma, et al.; Eur. J. Pharmacol.
406, 333 (2000),
Abstract;
Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review: I. Zs-Nagy, et al.; Arch. Gerontol. Geriatr.
11, 177 (1990),
Abstract;
