Useful as a control peptide in studies using D-JNKi1 (BML-EI355). This peptide is the cell transporter, and does not contain the JIP (JNK inhibitor peptide) sequence.
Product Details
| Sequence: | H-DPro-DPro-DArg-DArg-DArg-DGln-DArg-DArg-DLys-DLys-DArg-Gly-NH2 |
| |
| MW: | 1589.5 |
| |
| Formulation: | Lyophilized. |
| |
| Purity: | ≥98% (TLC) |
| |
| Appearance: | Solid. |
| |
| Solubility: | Soluble in Water. |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Store as supplied, at -20ºC for up to 1 year. Store solutions at -20ºC for up to 3 months. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Epidermal RAF prevents allergic skin disease: J. Raquz, et al.; Elife
5, e14012 (2016),
Application(s): Animal studies and inhibitor treatment,
Abstract;
Full Text
D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia: L. Hirt, et al.; Stroke
35, 1738 (2004),
Abstract;
Full Text
Use of cell-permeable peptides to prevent neuronal degeneration: T. Borsello & C. Bonny; Trends Molec. Med.
10, 239 (2004),
Abstract;
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia: T. Borsello, et al.; Nature Med.
9, 1180 (2003),
Abstract;
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death: C. Bonny, et al.; Diabetes
50, 77 (2001),
Abstract;
Full Text
