NAM is a highly potent and irreversible inhibitor of MAG lipase (IC50=155 nM) which covalently binds to a cysteine residue located near the fatty acid binding site. MAG lipase is an attractive drug target for pain disorders.
Product Specification
| Alternative Name: | NAM |
| |
| Formula: | C24H35NO2 |
| |
| MW: | 369.5 |
| |
| CAS: | 876305-42-9 |
| |
| Purity: | ≥98% (TLC) |
| |
| Appearance: | Colorless oil. |
| |
| Solubility: | Soluble in DMSO (>25mg/ml) and 100% ethanol (20mg/ml). |
| |
| Shipping: | Shipped on Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Use/Stability: | Store as supplied, at -80ºC for up to 1 year. Store solutions at -80ºC for up to 1 month. |
| |
| Technical Info/Product Notes: | Note: NAM is reactive with thiols, and thiols have been observed to interfere with in vitro assays involving NAM. For this reason, NAM may not be suitable for in vivo use. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
