NAM is a highly potent and irreversible inhibitor of MAG lipase (IC50=155 nM) which covalently binds to a cysteine residue located near the fatty acid binding site. MAG lipase is an attractive drug target for pain disorders.
Product Details
| Alternative Name: | NAM |
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| Formula: | C24H35NO2 |
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| MW: | 369.5 |
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| CAS: | 876305-42-9 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Colorless oil. |
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| Solubility: | Soluble in DMSO (>25mg/ml) and 100% ethanol (20mg/ml). |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Use/Stability: | Store as supplied, at -80ºC for up to 1 year. Store solutions at -80ºC for up to 1 month. |
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| Technical Info/Product Notes: | Note: NAM is reactive with thiols, and thiols have been observed to interfere with in vitro assays involving NAM. For this reason, NAM may not be suitable for in vivo use. |
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| Regulatory Status: | RUO - Research Use Only |
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