Inhibits the translocation of Akt.
Product Details
| Formula: | C21H14N2O2 |
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| MW: | 326.3 |
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| CAS: | 32387-96-5 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Determined by 1H-NMR. |
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| Appearance: | Light green solid. |
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| Solubility: | Soluble in DMSO (25 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Stereospecific inhibition of AMPK by (R)-crizotinib induced changes to the morphology and properties of cancer and cancer stem cell-like cells: T.H. Kim, et al.; Eur. J. Pharmacol.
911, 174525 (2021),
Abstract;
Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [ 177 Lu]Lu-PP-F11N: M. Grzmil, et al.; Theranostics
10, 10861 (2020),
Abstract;
Full Text
Systems kinomics demonstrates Congo Basin monkeypox virus infection selectively modulates host cell signaling responses as compared to West African monkeypox virus: J. Kindrachuk, et al.; Mol. Cell. Proteomics
11, M111.015701 (2012),
Application(s): Cell Culture,
Abstract;
Full Text
Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer: B.K. Lundholt, et al.; J. Biomol. Screen.
10, 20 (2005),
Abstract;
