Inhibits PKCα (IC50=43 µM) and PKCγ (IC50=50 µM) without inhibiting the δ, βI and βII isotypes.
Product Details
| Formula: | C16H18O8 |
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| MW: | 338.3 |
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| CAS: | 154675-18-0 |
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| Purity: | ≥95% (TLC) |
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| Appearance: | Orange solid. |
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| MeltingPoint: | 165-168°C |
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| Solubility: | Soluble in DMSO (25 mg/ml), ethanol (15 mg/ml warm) or water (10 mg/ml warm). |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Handling: | Product is subject to oxidation. Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C: Y. Kashiwada, et al.; J. Med. Chem.
37, 195 (1994),
Abstract;
