Peripheral decarboxylase inhibitor. Used with L-DOPA as a Parkinson's disease therapeutic.
Product Specification
| Formula: | C10H14N2O4 . H2O |
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| MW: | 244.2 |
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| CAS: | 28860-95-9 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in 100% ethanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation: A.N. Basma, et al.; J. Neurochem.
64, 825 (1995),
Abstract;
Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat: P. Cumming, et al.; Biochem. Pharmacol.
50, 943 (1995),
Abstract;
New and emerging strategies for improving levodopa treatment: E.S. Tolosa, et al.; Neurology
44, S35 (1994),
Abstract;
