Cyclooxygenase inhibitor selective for PGH synthase-2 over PGH synthase-1 (IC50=15-55 and 200-280 µM respectively).
Product Details
| Formula: | C13H12O3 |
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| MW: | 216.2 |
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| CAS: | 23981-47-7 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Off-white solid. |
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| MeltingPoint: | 171-173°C |
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| Solubility: | Soluble in DMSO (25 mg/ml) or ethanol (10 mg/ml warm). |
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| Shipping: | Ambient |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store solutions at -20ºC for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs: E.A. Meade, et al.; J. Biol. Chem.
268, 6610 (1993),
Abstract;
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